Well in this instance it won't, since the sort of people protesting are exactly who Trump's base want to see upset. Their anger is very much a feature of a Trump presidency rather than a bug as far as his voters are concerned.
And that's the other thing: the sheer ineffectuality of such protests. Trump knows these people will never vote for him, so he gives absolutely zero fücks what they think about anything. And as for what the contents of Islington think about his Presidency, I'm sure he gives a minus number of fücks.
This wasn't a pre-emptive protest about policies, this was just a mass hissy fit from self-indulgent virtue-signallers.